A Worldwide Leading PEG Supplier
Monodispersed PEG linkers are pure compounds with a single molecular weight. In contrast, polyPEG linkers contain variations in molecular weight with an average molecular weight. The use of polyPEG linkers in drug development has led to problems in biological applications due to steric hindrance and binding.
Efficiency and effectiveness are key concepts in the manufacturing of pharmaceutical drugs. The pharmaceutical industry is constantly seeking new ways to improve medications to allow for better patient consumption. One of the growing advancements in drug development is the PEGylation of these drugs to induce better results for patients. PEGylation involves the attachment of a […]
The introduction of a PEG linker to a molecule provides many benefits for pharmaceutical and biotech R&D due to its water solubility, lower toxicity and non-immunogenicity. The introduction of different functional groups to the end of a PEG linker allows for more site-specific reactions. For example, proteins have various amino acid residue that may be […]
With the success of the marketed ADC drugs, ADCETRIS and Kadcyla, the list of ADCs that are undergoing clinical trials has begun to grow. There are currently 40 ADCs in different phases of the clinical trial. Of the 40 ADCs being tested, there are 34 provided structures; 24 of these ADCs are linked to thiol […]
Powered by WordPress. AwesomeOne theme by Flythemes