Click Chemistry Becoming A New Popular Approach

By BroadPharm

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July 22, 2020

| Biotin Labeling, Drug Development / Delivery, Dye Labeling, PEG and Click Chemistry, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry, Product

University of Penn wrote this amazing article on Click Chemistry, a new popular approach in how we can find answers to how certain pathogens, including SARS-CoV-2, affects hosts and avoids detection by the immune system. Source: https://penntoday.upenn.edu/news/new-tool-cell-biologistsOur Click Chemistry Tools: https://broadpharm.com/web/products.php?category1=Click%20ChemistryImage Source: https://doi.org/10.1101/2020.04.07.030445 #ClickChemistry #PennState #research #PEGlinkers #PEGylation #PROTAC #dyelabeling #bioconjugation #chemistry #PEGsupply #PEGreagent #drugdiscovery […]

Click Chemistry and Diazo Transfer Method

By BroadPharm

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June 24, 2020

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| Biotin Labeling, Drug Development / Delivery, Dye Labeling, Oligonucleotides, PEG and Click Chemistry, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry, Product, Surface Modification, Uncategorized

Click Chemistry, coined by K. Barry Sharpless of Scripps Research, has been widely used in in developing new drug molecules and non-pharamceuticals. Chemists developed a new method called the “diazotransfer” reaction where they use fluorosulfuryl azide to convert primary amines into azides in a more quick, efficient and safe way under room-temperature conditions. It also […]

Some Findings About IMMU-132!

By BroadPharm

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May 28, 2020

| 1 Comment

| Biotin Labeling, Drug Development / Delivery, Oligonucleotides, PEG and Click Chemistry, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry, Product

2019 was a very exciting year with three ADC drugs approved by FDA, followed by one more new ADC, Sacituzumab Govitecan (IMMU-132) approved in 2020 from Immunomedics. IMMU-132, also known as Trodelvy, is an immune targeted therapy medicine for triple-negative breast cancer. The drug consists of sacituzumab and SN-38 with a linker in between. Sacituzumab […]

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