Nanomedical Diagnostics studied signal-to-noise ratio (SNR) in graphene biosensors to show that graphene-based platforms should be popularized for next generation diagnostics due to Field Effect Biosensing (FEB) based biosensors. A PEG linker was used in their solution for kinetic analysis. They created a portable, low-cost platform that has advantages in response time, fabrication ease, sensitivity […]
Recently published by the School of Medicine of Stanford University, researchers have been looking into new ways to improve stem cell therapy by decreasing the time, risk and cost. During the process, they have created an experimental design involving click-chemistry and glycoengineering to test different kinds of stiffness of the polymer coating in order to […]
Monodispersed PEG linkers are pure compounds with a single molecular weight. In contrast, polyPEG linkers contain variations in molecular weight with an average molecular weight. The use of polyPEG linkers in drug development has led to problems in biological applications due to steric hindrance and binding.
Efficiency and effectiveness are key concepts in the manufacturing of pharmaceutical drugs. The pharmaceutical industry is constantly seeking new ways to improve medications to allow for better patient consumption. One of the growing advancements in drug development is the PEGylation of these drugs to induce better results for patients. PEGylation involves the attachment of a […]
The introduction of a PEG linker to a molecule provides many benefits for pharmaceutical and biotech R&D due to its water solubility, lower toxicity and non-immunogenicity. The introduction of different functional groups to the end of a PEG linker allows for more site-specific reactions. For example, proteins have various amino acid residue that may be […]