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Category: Drug Development / Delivery

An Example of PEG Linker Used in Nanotechnology

By BroadPharm
|
April 15, 2020
| No Comments
| Biotin Labeling, Drug Development / Delivery, Dye Labeling, PEG and Click Chemistry, PEG Linker Chemistry

Nanomedical Diagnostics studied signal-to-noise ratio (SNR) in graphene biosensors to show that graphene-based platforms should be popularized for next generation diagnostics due to Field Effect Biosensing (FEB) based biosensors. A PEG linker was used in their solution for kinetic analysis. They created a portable, low-cost platform that has advantages in response time, fabrication ease, sensitivity […]

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Posted in Biotin Labeling, Drug Development / Delivery, Dye Labeling, PEG and Click Chemistry, PEG Linker Chemistry

Single-Cell Encapsulation via Click Chemistry Involving DBCO-PEG

By BroadPharm
|
March 11, 2020
| No Comments
| Biotin Labeling, Drug Development / Delivery, Dye Labeling, PEG and Click Chemistry, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry

Recently published by the School of Medicine of Stanford University, researchers have been looking into new ways to improve stem cell therapy by decreasing the time, risk and cost. During the process, they have created an experimental design involving click-chemistry and glycoengineering to test different kinds of stiffness of the polymer coating in order to […]

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Posted in Biotin Labeling, Drug Development / Delivery, Dye Labeling, PEG and Click Chemistry, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry Tagged clickchemistry, dyelabeling, peglinkers, pegsupply, pegvendor, polymer, research, stanford, stemcelltherapy

Monodisperse PEG in Drug Development

By BroadPharm
|
September 26, 2018
| 2 Comments
| Drug Development / Delivery, PEG Linker Chemistry

Monodispersed PEG linkers are pure compounds with a single molecular weight. In contrast, polyPEG linkers contain variations in molecular weight with an average molecular weight. The use of polyPEG linkers in drug development has led to problems in biological applications due to steric hindrance and binding.

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Posted in Drug Development / Delivery, PEG Linker Chemistry Tagged drug development, linker chemistry, monodisperse peg, pegylation 2 Comments

The PEGylated Drug

By BroadPharm
|
September 26, 2018
| No Comments
| Drug Development / Delivery, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry

Efficiency and effectiveness are key concepts in the manufacturing of pharmaceutical drugs. The pharmaceutical industry is constantly seeking new ways to improve medications to allow for better patient consumption. One of the growing advancements in drug development is the PEGylation of these drugs to induce better results for patients. PEGylation involves the attachment of a […]

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Posted in Drug Development / Delivery, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry

PEGylation Chemistry

By BroadPharm
|
September 26, 2018
| No Comments
| Biotin Labeling, Drug Development / Delivery, Dye Labeling, PEG and Click Chemistry, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry, Surface Modification

The introduction of a PEG linker to a molecule provides many benefits for pharmaceutical and biotech R&D due to its water solubility, lower toxicity and non-immunogenicity. The introduction of different functional groups to the end of a PEG linker allows for more site-specific reactions. For example, proteins have various amino acid residue that may be […]

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Posted in Biotin Labeling, Drug Development / Delivery, Dye Labeling, PEG and Click Chemistry, PEG in Antibody Drug Conjugates (ADC), PEG Linker Chemistry, Surface Modification
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