Man Made Adhesives using PEGs Modeled After Mussels


Marine mussels are able to adhere to a variety of surfaces in wet conditions through the byssus, a collection of tough, silky, wet fibrous strands. Researchers at UC Berkeley and Nanjing University had a goal to make man-made adhesives by mimicking the adhesion of Lysine-DOPA in marine mussels. This can help make products such as wound closing materials, self-healing hydrogels and bio-compatible adhesives. Fmoc-strategy was used to synthesize all the peptides with PEG Linkers followed by click chemistry. They have found that a specific increase in peptide length increases adhesion strength, but further increase in peptide length has no additional effect.

Source: https://lnkd.in/gdXN5Yp
Azido-PEG6-Acid: https://lnkd.in/gmx67-T
Fmoc-N-amido-PEG8-acid: https://lnkd.in/g-Y7mbc

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