Click Chemistry and Diazo Transfer Method


Click Chemistry, coined by K. Barry Sharpless of Scripps Research, has been widely used in in developing new drug molecules and non-pharamceuticals. Chemists developed a new method called the “diazotransfer” reaction where they use fluorosulfuryl azide to convert primary amines into azides in a more quick, efficient and safe way under room-temperature conditions. It also allows newly generated azides to used instantly without any further processing. The chemists at Scripps also used the technique to make triazole variants of a new anti-tuberculosis drug that contains 100 times increased potency and more efficient drug properties compared to the original molecule. Source: https://lnkd.in/gaRunVe

Here at BroadPharm, we provide a variety of Click Chemistry tools. You can check them out here at https://lnkd.in/gdvXiHP. You can also contact us for inquiries on custom synthesis projects. We would love to contribute to your research and discovery.

 

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